“Our new brand symbolizes the mission of our new and larger company foundation. We are making innovative strides to help our customers improve breathing-related healthcare, or perfect their scientific and environmental analytical solutions,” said Sharon Bracken, CEO, Perma Pure group.

While strengthening our core expertise in moisture control, we are actively engaged in providing more value to our partners so that they can focus on delivering the best analytical technology and life-saving equipment. 

Perma Pure’s rebrand reflects the larger role we intend to play to help the world breathe easier and be healthier. As we introduce our new look, we invite you to take advantage of our added expertise, improved operational capabilities, investment in innovation, and our customer-centric culture, all of which are backed by strong fundamentals in quality.

Fill the form below or contact us through one of the links to find more about precise humidity control, cost savings for our products you currently use and added capabilities of Perma Pure you can take advantage of.

The post Perma Pure helps the world Breathe Easier and Be Healthier appeared first on Perma Pure.

Perma Pure gas dryers are powered by Nafion tubing, which selectively removes water vapor from a gas sample. Because of Nafion polymer’s selectivity for water vapor, a Nafion dryer removes more moisture than other gas drying solutions while protecting analytes in the gas sample.

How It Works:​

A Perma Pure dryer moves water vapor out of the sample gas stream and into a counterflowing purge gas using the partial pressure of water vapor to drive the exchange.

Purge gas should be instrument quality air (-40°C dew point) or nitrogen flowing at two to three times the sample flow rate.​ If no purge gas is available, there are other purge gas configurations that can be used, for example pulling vacuum through the purge path.

While the partial pressure of water in the purge gas is less than in the sample gas, Nafion polymer will selectively transfer water vapor from the sample gas across its membrane and into the purge gas flow to be swept away. At the sample gas outlet, water vapor has been removed from the sample to achieve humidity levels as low as –45 °C dewpoint.​

Pros	Cons
Achieves sub-ambient humidity levels (as low as –45 °C dew point) depending on configuration Keeps analytes, including those that are water-soluble, in the gas sample Provides a consistent humidity level of the output gas No moving parts to wear out and no power required	Requires access to a dry purge gas, such as instrument quality air or use of another purge gas configuration

Also called a Peltier cooler, Peltier chiller, chiller, or thermoelectric chiller, these systems cool a sample gas by chilling it and condensing-out the moisture.

How It Works:​

A gas sample is sent through an impinger, which cooled by a Peltier module using the Peltier effect. Water in the gas sample condenses, and collects at the bottom of the impinger. Water collected in the impinger is drained away, perhaps using a peristaltic pump. This process of condensing-out the water in the sample yields a less humid gas sample at the output.

Pros	Cons
Provide a consistent and known humidity level (+4 C dew point) In CEMS applications, this is the industry standard for gas sample conditioning.	Can’t dry to humidity levels lower than +4 °C dew point If acidic gases are present, such as SOx, NOx, and HCL, +4 °C dew point may not be dry enough to prevent acids from forming and entering the analyzer. Highly water-soluble components in your sample may be lost to water that is condensed out of the sample. Requires periodic cleaning of impingers depending on operation Power required

Also known as a moisture trap, these devices remove existing water droplets from a gas sample. They ‘trap’ the water, but do not remove water vapor from the sample, which may condense at a later point.

How It Works:​

A gas sample is sent into the water trap. ​Any liquid water droplets in the sample will fall out due to gravity and collect at the bottom of the water trap. Before reaching the output, any excess water droplets in the gas stream will be caught by the baffle. ​At the output, the gas contains no liquid water. ​Water in the water trap can be drained by a peristaltic pump, or more commonly, by manually draining it after use.

Pros	Cons
Low-tech and inexpensive No moving parts to wear out and no power required	Can only remove already-condensed liquid  Water-soluble analytes will be lost in the water that is removed from the sample gas  Typically water is drained manually, which increases maintenance

Desiccants are hygroscopic materials that are used to remove moisture. Desiccant gas drying systems are essentially a cartridge filled with desiccant that a wet gas stream is passed through.

A wet gas sample is directed through the desiccant cartridge or desiccant canister. ​Inside, microporous ceramic beads (such as activated alumina, silica gel, molecular sieve, or another ceramic) will trap moisture in their voids, giving a drier sample gas at the output of the desiccant dryer.

While in operation, desiccants become progressively loaded with water, and must be periodically replaced or regenerated by heating the desiccant to evaporate the water.​

Pros	Cons
Low-tech and inexpensive  Achieves sub-ambient humidity levels No moving parts to wear out and no power required	Desiccants non-selectively remove water and other analytes from the gas stream Requires regular replacement of the desiccant over the life of the analyzer  Performance of desiccant degrades over time as it accumulates moisture, leading to inconsistent output humidity levels

This gas drying system dilutes a wet gas sample with dry air, so the gas mixture that reaches the analyzer has less moisture content.

A wet sample gas is diluted by mixing in dry air, such as instrument quality air, to a particular ratio (typically around 25:75, sample gas to instrument air). The analyzer detects the analyte at lower levels but reports the actual value, which is a multiplication of the analyte level detected by the percent volume of sample gas in the mixture that entered the analyzer.​

Pros

Cons

Low maintenance  Can achieve very low, sub-ambient, humidity levels depending on the configuration  No moving parts to wear out

A highly sensitive analyzer is required because the analyte becomes diluted in the gas sample. This requirement makes the configuration expensive. Stability of the dilution ratio is critical to proper calibration, and sometimes difficult to maintain since pressure and temperature of the system can affect the dilution ratio.  Requires access to a dry gas, such as instrument quality air, which may not be available in some operating environments.  Power required

• Can achieve sub-ambient humidity

  Can achieve sub-ambient humidity

• Consistent output humidity

  Consistent output humidity

• Analytes & water soluble analytes retained in sample

  Analytes & water soluble analytes retained in sample

• No moving parts

  No moving parts

• Low maintenance

  Low maintenance

• No power required

  No power required

• No instrument quality air or nitrogen required

  No instrument quality air or nitrogen required

• Total cost of ownership

  Total cost of ownership

Perma Pure MD Series and PD Series Gas Dryers

• Can achieve sub-ambient humidity

• Consistent output humidity

• Analytes & water soluble analytes retained in sample

• No moving parts

• Low maintenance

• No power required

  
  *Required if instrument air or nigtrogen isn't available

• No instrument quality air or nitrogen required

• Total cost of ownership

  $$

Thermoelectric Coolers

• Can achieve sub-ambient humidity

• Consistent output humidity

• Analytes & water soluble analytes retained in sample

• No moving parts

• Low maintenance

• No power required

• No instrument quality air or nitrogen required

• Total cost of ownership

  $$

Water Traps

• Can achieve sub-ambient humidity

• Consistent output humidity

• Analytes & water soluble analytes retained in sample

• No moving parts

• Low maintenance

• No power required

• No instrument quality air or nitrogen required

• Total cost of ownership

  $

Desiccant Dryers

• Can achieve sub-ambient humidity

• Consistent output humidity

• Analytes & water soluble analytes retained in sample

• No moving parts

• Low maintenance

• No power required

• No instrument quality air or nitrogen required

• Total cost of ownership

  $$$

Gas Dilution Systems

• Can achieve sub-ambient humidity

• Consistent output humidity

• Analytes & water soluble analytes retained in sample

  
  * at trace dilutions

• No moving parts

• Low maintenance

• No power required

• No instrument quality air or nitrogen required

• Total cost of ownership

  $$$$

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Polytube Dryer (PD Series​)

Contains multiple Nafion  tubes, and thus is our dryer with the highest drying capacity. Recommended for flow rates up to 40 lpm.

View PD Series  Gas Dryers >

Monotube Dryer (MD Series)

Contains a single Nafion  tube. Recommended for flow rates up to 4 lpm.

View MD Series  Gas Dryers >

All Perma Pure Products

Including all gas dryers, and for CEMS applications, Baldwin Thermoelectric Coolers and sample conditioning systems.

View all Perma Pure products >

The post Pros and cons of top gas drying methods for gas analyzers appeared first on Perma Pure.

湿度太大是一个常见问题

空气（或气体）只能容纳这么多水蒸气。根据温度和压力等外部因素，水蒸气会冷凝并产生诸多问题。冷凝水雾传感器会导致设备过早磨损或冷凝水进入采样管线或呼吸气体回路。

因此，通常我们所面临的挑战即是防止冷凝的发生。当您尝试从气样中去除水蒸气时，水蒸气就需要一个去处。如果系统外部的环境空气湿度低于气样湿度，则可以将系统设计以进行湿度转移，或在水蒸气冷凝时用水槽收集水分。请切记，收集在水槽中的水被视为生物废物，需要医疗专业人员以某种方式进行处理，因而给他们繁重的工作带来负担。然而，水槽的问题在于它在收集水的同时也会截获有价值的分析物，使您遭受分析质量不佳的风险。如果您试图将水蒸气转移到环境空气中，那么当环境空气湿度很高时便会出现一个特别的问题。此时，可以使用干燥的吹扫气从待分析的湿气中去除水蒸气。

湿度小也是一个挑战

在某些应用领域中，例如给予治疗用气体时，湿度水平可能太低。毕竟，人体肺部（体温、环境压力和气体饱和度或BTPS）在100％的相对湿度和37°C的温度下方能运作。因此，挑战就变成了如何向气体中添加水蒸气或如何与另一种湿度更高的气流交换水蒸气。

意识到这两点是设计能够使湿度水平刚刚好的医疗器械的第一步。

The post 工程师面临哪些湿度方面的挑战？ appeared first on Perma Pure.

什么是Nafion?

从专业上讲，Nafion是四氟乙烯和一种磺酸组分的共聚物。简单来说，Nafion是基于PTFE聚合物的化合物，与Teflon（特氟龙）非常相似。它是具有离子通道的合成材料。这些离子通道可通过该材料转移特定物质，包括水和酒精。除具有离子通道外，它还是无孔材料，实际上具有疏水性。由于Nafion管无孔，因而远远优于其他膜材料。它连微孔都没有，您大可放心，即使是二氧化碳之类的重要分析物也无法通过。

为什么Nafion在医疗器械中受到重视?

在某些医疗程序中，其目标是保留分析物的同时将水分从气样中去除。例如，在二氧化碳分析中，人的呼吸被采样到二氧化碳波形图中以测量EtCO2。病人的呼吸中含有大量水蒸气，会凝结在设备中，从而导致读数不准确，甚至可能导致设备过早磨损。如果将多孔材料用于采样管线，会除去一些水蒸气，但同时也会有去除重要分析物的风险。使用Nafion管时，只有水分子可通过离子通道进入周围空气中，而全部二氧化碳均可保留在管中。

Nafion还用于在采样管线中增添水蒸气

Nafion管在允许水蒸气移至外部的同时，还可将水蒸气添加至管中。例如，一氧化氮和氧气之类的治疗用气体对于患者而言可能非常干燥且不舒服。通过在Nafion管外部产生高湿度并让干燥气体通过，水分子可通过离子通道，并于此吸收到干燥气流中。由于Nafion离子通道具有非常高的选择性，因此只有水可以通过，而大多数污染物则不能。

Nafion的独特性能使其成为解决许多湿度难题的理想之选。

The post Nafion™如何解决湿度方面的挑战？ appeared first on Perma Pure.

湿气: 为什么要去除它?

测试或分析病人的呼吸有助于医疗护理专业人员做出正确的诊断和快速识别呼吸疾病，然而呼吸样气中的水分会造成问题。水分会损坏传感器，而这反过来又会降低测试精度，甚至损坏传感器使其无法修复。这可能会让医疗护理者感到沮丧和恼火。去除湿气可以为患者提供更准确的结果和更好的结果。

移除多少湿度才足够?

当从呼吸样气中除去水分时，经常使用无凝结这个术语。这只是意味着呼吸样气中的水分含量足够低，以确保在普遍条件下不会发生冷凝。

根据应用的不同，工程师和医疗护理专业人员的目标更高。他们可能想要除去比呼吸样气无凝结要求更多的水分。这就需要确保不会发生意外的冷凝。此外，呼吸测试和其他应用的最新技术受益于有特定水平的相对湿度。

什么程度的湿度水平移除是可能的?

使用Nafion管，高达90%的水分从病人的呼吸可以被移除。对于工程师和设计师来说，这意味着无意的冷凝不会发生，他们可以达到严格的水分控制规格。

快速标记:当讨论水分和水蒸气时，要用到几个术语。相对湿度是空气中水蒸气的百分比，与空气在该温度下所能容纳的水蒸气总量相比，它会随着温度和压力的变化而波动。露点是空气达到100%相对湿度所必须的温度，它更多的是一个绝对术语。在博纯，当我们说您Nafion管可以去除90%的水分含量，我们的意思是它作为一个绝对值。

为什么精确的湿度控制很重要?

对于许多传感器来说，必须在一个特定的水平，要最有效地分析气体、相对湿度，或空气中水蒸气的百分比。例如，用于气体的电化学传感器需要在15%到90%之间的相对湿度才能达到最佳性能。如果没有达到这个水平，电解质中的水分含量可能会受到负面影响。可以证明，光学传感器受到湿度的影响最大，因为被分析的气流中的水蒸气数量决定了信噪比。一些工程师已经提出了算法和捕捉信息的聪明方法-但湿度控制可能是他们开发的一个关键部分。

精确的水分控制可降低意外移除呼吸样气中分析物的风险(特别是含有诊断价值信息的分析物)。不完整的样气可能会对病人的病情做出不准确的描述，延误合适的护理。

Nafion管是如何移除90%的水汽?

从气流中去除一定量的水分可以通过专业工程设计来实现。Nafion管与环境条件达到平衡。将水分降低至低于周围环境条件水平的一种方法是，使用露点低于样气的吹扫气体进行反吹。通常，吹扫气体将围绕Nafion管在样气的相反方向流动。这样做，通过Nafion管您将创建一个极低的湿度。

通过这种方式使用Nafion管，您可以在更精确的水平上去除水分-达到您的设备最佳性能所需的湿度水平。反之，设备将提供更准确的数据分析结果，从而提高患者的治疗效果。

The post 从患者的呼吸样本中去除90％水分的秘密武器 appeared first on Perma Pure.

湿度、相对湿度和露点之间有何区别？

简而言之，湿度是指空气中存在的水蒸气的量。温度和压力等环境条件均会影响湿度。例如，空气越热，它可以容纳的水蒸气量就越大。

相对湿度是指在给定的环境条件下，空气中水蒸气量与空气可容纳的最大水蒸气量之百分比。因此，如果相对湿度为50％，则意味着在该温度和压力下，空气可容纳的水蒸气量是目前水蒸气量的两倍。如果空气被加热（保持压力恒定），则相对湿度将下降。

露点是指大气温度，低于此温度水滴会凝结并形成露水。当环境温度与露点相同时，相对湿度为100％。在春季和夏季，您经常会听到天气预报员提到露点。理解露点的一种简单方法就是考虑露点为50华氏度时的某个春日。白天，阳光使空气温度升高至60华氏度左右。晚上，空气变凉。当温度达到50华氏度时，空气就会达到饱和状态。当温度降至50华氏度以下时，水蒸气会凝结并在草坪和其他物体表面上形成露水或液态水。清晨的阳光使空气重新加热时，露水就会重新被吸收到空气中，而草坪变干。

设计医疗器械时何种测量最佳？

设计时，露点优先于相对湿度纳入考量。这是因为相对湿度随温度变化而波动，而露点则是绝对测量值。例如，如果呼吸样本通过加热管并被加热，相对湿度就会发生变化，但空气中的实际水蒸气量保持不变。如果使用露点来测量呼吸样本，即使温度波动，它也将保持不变。

The post 湿度对医疗器械的影响：第一部分 appeared first on Perma Pure.

医疗环境中存在的细菌

医疗环境中存在的细菌可能不仅难闻。某些类型的细菌还可能对有害患者健康，甚至致命。这就是为何医护人员始终对细菌感染保持高度警惕的原因。

在医疗环境中，呼吸疗法是细菌滋生和感染传播特别需要关注的方面。例如，鼓泡器通常用于呼吸疗法，以在呼吸气体到达患者之前为其增加湿度。然而，鼓泡器可能是细菌污染的主要来源。尽管几乎所有的鼓泡器都使用无菌水/蒸馏水，但当打开起泡器的盖子以注满水时，会引入尘粒和其他环境微粒。当带有细菌的气泡破裂时，它可能引起细菌污染，并可能导致病原体的传播。

医院感染，换言之，即医院获得性感染，由于其危险性，成为人们高度关注的话题。它们可能导致高代价的死亡率和发病率，而这对于我们的医疗系统而言在处理上是个难题。实际上，在医院获得性感染的患者中，医院获得性肺炎是主要的致死因素，占所有医院获得性感染的22％。这就是为何医护人员、医疗器械制造商和联邦机构都致力于降低医疗环境中细菌感染风险的原因。为此，医院也被给予严格审查。

重要的是要知道，周围环境中理想的相对湿度应为40％到60％。若相对湿度过低或过高，病毒感染的风险就会增加。这就是为何在较冷的月份病毒感染会激增的原因。据若干研究结果表明，当相对湿度较低时，小鼠中的感染率会增加。

降低感染风险

疾病控制中心可提供有关如何保持卫生行为以减少污染风险的指南，但要完全消除细菌实属困难。多年来，食品药品监督管理局和医疗器械制造商已召回诸多有细菌感染危险的产品。

控制细菌的途径

控制细菌的一种途径是控制导致细菌滋生的条件。虽然不同类型的细菌需要不同的温度和其他条件才能生长和存活，但它们也需要养分、水分或湿气。若湿气不受控则会促使细菌（包括对人体有害的细菌）滋生。控制湿气可确保其仅在必要时存在，并在不必要时去除，进而可以控制细菌的生长。

控制医疗环境中的湿度

由于湿度不受控可导致意想不到的危险细菌滋生，进而导致接受呼吸治疗的患者死亡和发病，因此，控制湿度至关重要。设计用于呼吸治疗的医疗设备时，找到可靠的方法以控制湿度对减少甚至防止细菌生长大有帮助。进而可促使环境更卫生，患者预后更佳（以及难闻气味更少）。

The post 想要控制细菌滋生？控制湿度！ appeared first on Perma Pure.

湿度会影响分析准确度并损坏设备

在医疗过程中，麻醉师会对患者呼出的二氧化碳浓度进行测量。他们这样做的目的是跟踪患者的肺部健康，并在适当的时间确定适当的行动方案。那这是如何实现的呢？患者的呼吸通过采样管线到达二氧化碳描记图，或换言之，即是二氧化碳分析仪。

这不仅仅是手术。利用患者的呼吸可进行越来越多的医学检测和诊断。与其他类型的检测相比，检测患者的呼吸状况以监测各种问题（包括哮喘、胃肠道问题和癌症）通常具有较低创伤性和成本的方法。

那么，水蒸气在何处起作用呢？人类的呼吸中含有很多水分。即使只是呼吸到镜子上，也可看到水蒸气在镜子表面凝结。如果水蒸气未从患者的呼吸样本中除去，则可能会进入分析仪。这就是问题所在。水蒸气会导致结果不准确并损坏医疗设备，常常导致可怕的后果。在进行分析之前，除去湿气或水蒸气可获得更准确的结果。

湿度较低面临的其他挑战

呼吸干燥的空气会令人感到不适。那是因为人的肺部相对湿度通常为100％。向患者输送干燥的治疗用气体会引起不适并使粘膜变干。在几种情况下都需要加湿治疗用气体，这样可提升患者的舒适度并使疗效更佳。

控制湿度的许多方法都无效或需要维护

为了去除冷凝水，有时会在连接患者和分析仪的采样管线中放置水槽。但这并不是万无一失的解决方案。如果气体通过水槽后才发生凝结，这种方法即告无效。更成问题的是，当水槽移动或受到干扰时，会将一团液体带进设备，因此可能会造成设备损坏。有时水槽还会触发低限警报，需要护士的注意以将水清除。护士可能会产生警报疲劳，由于感觉超负荷而对警报声不敏感。水槽中积水又会引发另外一个警报，这样更加可能导致警报疲劳。

有些人可能会使用过滤器来尝试管理湿度。但是，过滤器需要花时间来更换，如果它们没有定期更换，您可能会获得较差的质量结果。

那么，湿度可以控制吗？

答案是肯定的！博纯的Nafion聚合物管可以选择性地通过膜来传输水分子，并从湿气流中去除多达90％的水分。或者，它可用以将水蒸气加入到患者治疗用干燥气流中。这意味着：

• 测试结果精准
• 可防止设备损坏（从而节省更多成本）
• 患者舒适度增加
• 患者预后更佳

这些优点可帮助每位患者呼吸更轻松、更健康。

The post 为何湿度很重要？ appeared first on Perma Pure.

As a valued partner to Perma Pure, we would like to take a moment to update you on the actions our organization is taking to ensure the safety of our employees and the continuity of business for our customers.

Employee Health and Safety is our Top Priority
To ensure the health and safety of our people we have taken the following actions:

• Working with our employees on a continual basis in alignment with World Health Organization (WHO).  This includes translating WHO recommendations for employees whose primary language is not English.
• Secure additional cleaning products in support of a healthy, clean work environment.
• Cancel unnecessary travel.

Continuing to Serve our Customers
We recognize that we serve customers whose products make an impact on people and communities all over the world.  In light of the issues caused by COVID-19, we recognize the demand for our technology will increase during this time.  As such, we have taken the following measures:

• Increase safety stock of raw material and specialized tooling to increase speed and capacity.
• Redistribution of team members to meet urgent customer orders and requests.
• Increase staffing levels of critical operational positions.

Please contact a Perma Pure team member with any additional questions or concerns.  You can reach our team directly at CustomerService@permapure.com.

We thank you for your loyalty and we look forward to continuing the great work we do, together.

About Perma Pure LLC
Perma Pure LLC, a Halma company, is a leading manufacturer of high-performance gas conditioning solutions, including dryers, humidifiers, filters, coalescers, specialty scrubbers and complete sample conditioning systems.  Headquartered in Lakewood, NJ, and with service and support centers located in India and China, the Company is the exclusive manufacturer of tubing solutions using Nafion polymer originally developed by DuPont.  With products that deliver best-in-class quality and reliability, Perma Pure is the trusted choice for market leaders in medical, scientific, and environmental monitoring markets.  The Company’s products contribute to the health, safety, and well-being of millions of people around the world.  Perma Pure LLC is ISO certified to 9001:2015, 13485:2016, and is FDA registered. For more information, visit ppchina.wpengine.com.

The post How Perma Pure is Responding to COVID-19 appeared first on Perma Pure.

LAKEWOOD, N.J., Feb. 7, 2020 – Perma Pure LLC, a global leader of gas conditioning solutions for medical, scientific and environmental monitoring applications, today announced that the Company will be exhibiting at MD&M West, Feb. 11-13, in Anaheim, CA.  Visitors to the Perma Pure exhibit, 961, will learn about the Company’s high-performance moisture management solutions for medical applications including capnography, anesthesia monitoring, pulmonary function testing, inhaled gas therapy and more.

MD&M West, now in its 35th year, is where engineers and executives from across the globe converge before going on to change the lives of patients. In addition to the three-day conference covering medtech, 3D printing, and smart manufacturing, the event offers the opportunity to meet suppliers and experts leading the charge to disrupt healthcare.

From decreasing measurement accuracy to increasing patient discomfort, condensation from exhaled breath can have adverse implications. Perma Pure’s Nafion tubing can help can overcome these challenges, improving accuracy by removing moisture interference, retaining breath samples and protect medical monitoring equipment.

About Perma Pure LLC
Perma Pure LLC, a Halma company, is a leading manufacturer of high-performance gas conditioning solutions, including dryers, humidifiers, filters, coalescers, specialty scrubbers and complete sample conditioning systems.  Headquartered in Lakewood, NJ, and with service and support centers located in India and China, the Company is the exclusive manufacturer of tubing solutions using Nafion polymer originally developed by DuPont.  With products that deliver best-in-class quality and reliability, Perma Pure is the trusted choice for market leaders in medical, scientific, and environmental monitoring markets.  The Company’s products contribute to the health, safety, and well-being of millions of people around the world.  Perma Pure LLC is ISO certified to 9001:2015, 13485:2016, and is FDA registered. For more information, visit ppchina.wpengine.com.

The post Perma Pure to Join Medical Equipment Industry Leaders at MD&M West appeared first on Perma Pure.